Comments on: L-Glutamine Benefits Leaky Gut & Metabolism https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/ Dr. Axe is a Certified Nutrition Specialist, expert in Natural Medicine, a speaker for Fortune 500 Companies (Nissan, Whole Foods) and a doctor of chiropractic. Tue, 06 Dec 2022 13:07:56 +0000 hourly 1 By: Denise Marie Hardman https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-31634 Wed, 25 Mar 2015 22:59:34 +0000 https://draxe.com/?p=16412#comment-31634 Does L-Glutamine help to reduce the symptoms of Restless Leg Syndrone?

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-31474 Mon, 23 Mar 2015 19:08:03 +0000 https://draxe.com/?p=16412#comment-31474 In reply to Betty Jo Woodcock.

I would look for a maximized living chiropractor in your area and also check this out:
You may also benefit from a vitamin B12, omega d3 supplements and a diet higher in fat and low in sugar

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-31322 Fri, 20 Mar 2015 20:36:36 +0000 https://draxe.com/?p=16412#comment-31322 In reply to Sharon.

I would consult with your physician

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By: Betty Jo Woodcock https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-31168 Tue, 17 Mar 2015 01:46:47 +0000 https://draxe.com/?p=16412#comment-31168 I have peripheral neuropathy, which is quite painful. Also have Charcot’s foot on the left. A friend suggested L-Glutamine Powder. I have taken it 3 times a day for only one day. So far, the foot pain has decreased and I hope that it is due to the powder. Any suggestions would be appreciated.

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By: Amy https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-31128 Mon, 16 Mar 2015 00:08:18 +0000 https://draxe.com/?p=16412#comment-31128 Very well written and informative article. My son has multiple food allergies and I spend a good amount of time researching natural healing options for him. This seems like a great option. But I must say I am confused. In my research I have run across doctors who claim that foods high in glutamate should be avoided. Why are there so many differing opinions? eg

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By: Sharon https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-31108 Sun, 15 Mar 2015 02:33:38 +0000 https://draxe.com/?p=16412#comment-31108 Hi Dr Axe

Is L-Glutamine safe when pregnant and breast feeding?

Thanks :)

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By: Scarlett https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-31105 Sat, 14 Mar 2015 22:28:54 +0000 https://draxe.com/?p=16412#comment-31105 Quite shocked and very disappointed that this article doesn’t discuss side effects to taking L-Glutamine. I had severe side effects, including insommnia, loss of appetite, and (bizarrely) a fear of going out and confronting problems/Iissues that arose with other people. I mentioned these symptoms to a friend and she had exactly the same experience. Both pf us were taking the supplement prescribed by our respective naturopaths. I’m disappointed because I expected to read more responsible advice than has been given here. People should be helped to become aware of the detrimental effects of supplements as well. This is a very powerful supplement and needs to be respected.

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-30935 Tue, 10 Mar 2015 20:29:02 +0000 https://draxe.com/?p=16412#comment-30935 In reply to Sharon GoddardWa.

I would consult with your physician

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By: Sharon GoddardWa https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-30856 Tue, 10 Mar 2015 02:21:55 +0000 https://draxe.com/?p=16412#comment-30856 Want to make sure L Glutamine is ok for type 1 diabetic.

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-30690 Thu, 05 Mar 2015 17:34:03 +0000 https://draxe.com/?p=16412#comment-30690 In reply to Michelle.

I would follow dosage recommendations on the bottle

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By: Michelle https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-30530 Tue, 03 Mar 2015 18:05:56 +0000 https://draxe.com/?p=16412#comment-30530 I have just purchased a few supplements that you suggest for leaky gut (Qucertin, Licorice Root, Papaya Digestive Enzymes, etc.) but since I’ve never taken L-Glutamine before and you suggest powder if this supplement dosage would be fine? Its 1500 mg’s in capsule form? Also how long should you remain on these supplements to repair gut health?

Dietary Supplement•1500mg Dose to Prime Muscles for Workouts
•Provides Anti-Catabolic Effects & Supports Muscle Function
•Supports Faster Recovery After workouts
Glutamine is one of the most abundant amino acids found in muscles. It is involved in protein synthesis and plays an important role in hydrating muscle cells. With this amino acid’s great benefits in the body, it will support muscle function.

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-30286 Thu, 26 Feb 2015 16:45:44 +0000 https://draxe.com/?p=16412#comment-30286 In reply to Christine.

Try starting with 1g once a day and see how your body does with it. Also check out my leaky gut support formula: http://store.draxe.com/products/leaky-gut-support

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By: Christine https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-30105 Tue, 24 Feb 2015 16:42:24 +0000 https://draxe.com/?p=16412#comment-30105 I am trying to heal up a leaky gut, but when I tried glutamine (5g once a day) I had the worst constipation I have ever had. (Similar effect with high quality gelatin – I don’t have the time to make bone broth.) I tried adding a stool softener, adding pectin for soluble fiber, lots of water, etc. and I already take a probiotic, but the only thing that helped was a laxative – not fun! Is there any way to take this stuff to avoid severe pain and a non-working digestive tract?

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-29944 Fri, 20 Feb 2015 21:48:51 +0000 https://draxe.com/?p=16412#comment-29944 In reply to Lisa H.

Try searching for a physician who practices functional medicine

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By: Lisa H https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-29795 Wed, 18 Feb 2015 00:15:49 +0000 https://draxe.com/?p=16412#comment-29795 How do I find a Dr. in my area that treats like Dr. Axe does? Is it Fundamental Medicine? I need a Dr. who specializes in an auto-immune hyper-thyroid condition. I am in the Seattle, WA area.

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-29785 Tue, 17 Feb 2015 23:12:46 +0000 https://draxe.com/?p=16412#comment-29785 In reply to Kristina.

Typically your body only needs a max of 10-15g daily

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By: Kristina https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-29433 Tue, 10 Feb 2015 17:29:22 +0000 https://draxe.com/?p=16412#comment-29433 Hi Dr. Axe, i have been trying to heal my gut since July 2014, i have cut out grains, gluten, soy, wheat but still eat some dairy. I have also been taking 3-7 HCL pills depending on the meal I am eating. I take a propiotic every day in the AM and take oil of oregano once at night. i just received my NOW brand powder L-Glutamine and i had read to take 40g a day so last night I had 10g in a smoothie before supper. After supper I had another 10g in some juice. This morning I had 10g more in some water with some fruit. It’s lunch time so I was about to have 10 more grams. Now I read this and I am starting to worry about how much I’ve taken! I wonder why there is such a discrepancy on what sites recommend. If i am fine taking 40g a day should I continue or no? I am 5’5″ 115 lb femaie.

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-28474 Fri, 23 Jan 2015 20:03:30 +0000 https://draxe.com/?p=16412#comment-28474 In reply to Laura.

If you feel that 1g is doing nothing, try increasing to 1.5g slowly and see how your body does over a period of time. If it tolerates it well, after a week or 2, try adding another .5g

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By: Laura https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-28443 Fri, 23 Jan 2015 03:39:21 +0000 https://draxe.com/?p=16412#comment-28443 Hi Dr. Axe – sure hoping you see this; I can’t seem to find an answer to this question: I had been taking just 1g of l-Glutamine and wasn’t notcing anything so did some research about dosages. Found your blog among others that suggests it is quite safe at higher doses, say 3-5g 2-3 times per day. So one day recently I took 4g on an empty stomach, followed by a smoothie about an hour later. Two hours after taking the supplement I was doubled over with diarrhea and vomiting. It was very alarming. Obviously that dose didn’t work for me, but what I wish I knew is what might be going on in my gut to have caused this reaction? Lastly, how would you recommend I titre my doses in the future? Thanks so much!

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-28071 Mon, 12 Jan 2015 16:55:04 +0000 https://draxe.com/?p=16412#comment-28071 In reply to Karen.

It is possible

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By: Karen https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-27894 Tue, 06 Jan 2015 15:53:49 +0000 https://draxe.com/?p=16412#comment-27894 I read in a magazine article recently that glutamine can help with weight loss. Is this true?

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-27700 Fri, 02 Jan 2015 22:33:00 +0000 https://draxe.com/?p=16412#comment-27700 In reply to Krissy.

I would do lots of organic, grass fed meat, steamed vegetables, and get more probiotics in your diet

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By: Greg https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-27666 Fri, 02 Jan 2015 01:25:25 +0000 https://draxe.com/?p=16412#comment-27666 In reply to nancy.

Search the internet for deals and buy it in powder form that is cheaper. I just bought some a while back and it wasn’t anywhere near $42. Hope this helps.

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By: Teacher Randall https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-27522 Mon, 29 Dec 2014 04:49:17 +0000 https://draxe.com/?p=16412#comment-27522 Hey Dr. Axe you can’t do this, this is the internet. A website with actual research cited for claims made is breaking the unwritten rule of the internet. All articles must make at least ten claims per one citations, and that citation must be to another website which must have another website as its source never reaching an actual research paper. lol

but besides that great job! :D.

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By: Rose https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-27465 Thu, 25 Dec 2014 17:52:20 +0000 https://draxe.com/?p=16412#comment-27465 In reply to nancy.

Powder city.com sells it in bulk powder, they ship free and also have a 10% off coupon. 1 kilo approx. $ 27.00. That’s a lot of L Glutamine.
Good Luck, Rose !

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By: Laura https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-27408 Tue, 23 Dec 2014 02:09:53 +0000 https://draxe.com/?p=16412#comment-27408 Dr. Axe – I have Pure Encapsulations brand of L-Glutamine capsules and had been taking 1g/day until I read this article. Am trying to heal a leaky gut so planned to work my way up to 5g twice a day. Took 4g the other morning and within 2 hours was doubled over with vomiting and diarrhea. Obviously I need yo back off on the dosage, but I have to say, the reaction scared me given how safe this supplement is supposed to be. Can you tell me why I might have experienced that reaction and how I might titrate the dosage in the future (assuming I am brave enough to try again!)

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By: Krissy https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-27343 Thu, 18 Dec 2014 21:08:50 +0000 https://draxe.com/?p=16412#comment-27343 I’ve tried L-Glutamine but get sinus inflammation/migraines every time (my default reaction). Same with bone broth. I am sensitive to almost everything I eat so eat AIP and take entirely too much silver just to get by. I believe it’s leaky gut but all the best healers make me sick. Any other suggestions? Glutamine sounded like it would be the thing to fix me, but no dice. (Hashimoto’s for 15 years and hypothyroid before that, Reynaud’s syndrome, fatigue, brain fog, constant sinus battles, pain, neuropathy in all limbs and lately numbness in face) Thank you.

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26941 Wed, 03 Dec 2014 02:21:15 +0000 https://draxe.com/?p=16412#comment-26941 In reply to Jill Nau.

I would consult with your physician to ensure it does not

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By: Jill Nau https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26738 Thu, 27 Nov 2014 17:31:33 +0000 https://draxe.com/?p=16412#comment-26738 Would glutamine interfere or be bad to take with any medications?

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By: nancy https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26712 Thu, 27 Nov 2014 00:48:49 +0000 https://draxe.com/?p=16412#comment-26712 My local heal food store highly recommended this to me last Saturday also, but I was at my limit financially, so I didn’t buy it.
We are on a very tight budget and just don’t have the $42 to buy the one you use.
Can you suggest a less expensive brand?
I’m almost 62 and have been a T1 Diabetic for over 46 years and have had digestion issues since before then.
Thx for any recommendations.
Happy Thanksgiving to you all!

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26693 Wed, 26 Nov 2014 17:06:29 +0000 https://draxe.com/?p=16412#comment-26693 In reply to Denise Herrera.

I would consult with your physician

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By: Denise Herrera https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26681 Wed, 26 Nov 2014 14:42:44 +0000 https://draxe.com/?p=16412#comment-26681 Is this safe to take during pregnancy?

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By: Connie Markley https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26672 Wed, 26 Nov 2014 03:58:30 +0000 https://draxe.com/?p=16412#comment-26672 Is there any connection with MSG?

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26628 Wed, 26 Nov 2014 02:30:03 +0000 https://draxe.com/?p=16412#comment-26628 In reply to Amy.

Either form is fine

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By: Amy https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26616 Wed, 26 Nov 2014 00:02:07 +0000 https://draxe.com/?p=16412#comment-26616 Is it okay to take the tablets instead of powder? If, no – why not? Thx!

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26154 Wed, 19 Nov 2014 20:41:56 +0000 https://draxe.com/?p=16412#comment-26154 In reply to Kaye.

I’ve never heard of it having this type of effect so I don’t think that would be the culprit. I would try to get a little more movement in throughout the day and not sit or stand for long periods of time.

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-26129 Wed, 19 Nov 2014 16:38:20 +0000 https://draxe.com/?p=16412#comment-26129 In reply to Anh.

I would consult with your physician to make sure there are no contraindications. Also check this out: https://draxe.com/health/natural-ways-to-lower-blood-pressure/

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By: Anh https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-25692 Fri, 14 Nov 2014 01:17:50 +0000 https://draxe.com/?p=16412#comment-25692 Hi Dream.Axe, I’m currently taking 3 different medications for high blood pressure. If I take L-Glutamine, is it going to raise my blood pressure. Thank you.

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By: Kaye https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-25672 Thu, 13 Nov 2014 16:52:04 +0000 https://draxe.com/?p=16412#comment-25672 Hi Dr. Axe,
I have been taking l-glutamine long term, for over a year per a nutrition coach…2 grams, 3 x daily. Since July, I have had this mystery edema occuring only in my legs. I am super-healthy and eat super-healthy, labs point nowhere, and can’t seem to attribute this to anything else. Could my long term use of l-glutamine be the cause?

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By: gary malcik https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-25546 Wed, 12 Nov 2014 04:53:19 +0000 https://draxe.com/?p=16412#comment-25546 stomach lining and L glutamine

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-24059 Tue, 21 Oct 2014 16:26:10 +0000 https://draxe.com/?p=16412#comment-24059 In reply to Christa.

It may compete with others but food helps increase glutamine absorption overall, regardless. I am coming out with a leaky gut supplement that will be tied to an amino acid so that it does not have to be taken with food in order to reach full absorption potential.

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By: Christa https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-23963 Mon, 20 Oct 2014 17:30:57 +0000 https://draxe.com/?p=16412#comment-23963 I have always read that glutamine should NOT be taken with a meal that contains protein, as it has to compete for absorption with the other amino acids. Therefore it should be taken on an empty stomach. You have recommended to take glutamine with food. Is there a particular reason for this?

Thanks!

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-23468 Sun, 12 Oct 2014 15:54:53 +0000 https://draxe.com/?p=16412#comment-23468 In reply to Islam.

I prefer this supplement: http://amzn.to/XBMeHn

The highest L-glutamine foods include:

1. Bone Broth

2. Grass-fed Beef

3. Spirulina

4. Chinese Cabbage

5. Cottage Cheese

6. Asparagus

7. Broccoli Raab

8. Wild Caught Fish (Cod, Tuna and Salmon)

9. Venison

10. Turkey

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By: Islam https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-23364 Sat, 11 Oct 2014 13:41:14 +0000 https://draxe.com/?p=16412#comment-23364 Dr. Axe many thanks for your opinion and great informative articles you publish. With regards to L-Glutamine Supplementing, what do you think of Glutamine tablets like GNC Glutamine tablets? And also, what would you recommend for Paleo Nutrition enthusiasts when eating natural food sources for Glutamine, apart from Raw cultured Dairy sources?

Many thanks and all the best!

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By: kim https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-23352 Fri, 10 Oct 2014 21:09:44 +0000 https://draxe.com/?p=16412#comment-23352 In reply to Dr. Josh Axe.

Ok tyvm

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-22933 Thu, 02 Oct 2014 01:09:34 +0000 https://draxe.com/?p=16412#comment-22933 In reply to kim.

I haven’t read any studies that have stated that but regardless, vitamin B12 is very beneficial to consume.

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By: kim https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-22896 Wed, 01 Oct 2014 15:51:15 +0000 https://draxe.com/?p=16412#comment-22896 I read somewhere that taking b12 with the l glutamine will help with build up with the product is this true if so how much b12 do I take ty so much

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-22197 Wed, 17 Sep 2014 17:07:39 +0000 https://draxe.com/?p=16412#comment-22197 In reply to Cheryl.

About 1 tsp

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By: Cheryl https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-22194 Wed, 17 Sep 2014 16:15:32 +0000 https://draxe.com/?p=16412#comment-22194 Approximately how many teaspoons would 5 grams be?

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By: Dr. Josh Axe https://draxe.com/nutrition/l-glutamine-benefits-side-effects-dosage/#comment-22156 Tue, 16 Sep 2014 16:05:39 +0000 https://draxe.com/?p=16412#comment-22156 In reply to ghada.

If trying to heal leaky gut, I would do both. I personally consume a L-glutamine supplement and bone broth on a daily basis. Here are recipes on how to make bone broth:
https://draxe.com/recipes/chicken-bone-broth-recipe/
https://draxe.com/recipes/beef-bone-broth/

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